Lifestyle

Researchers use precision medicine to reverse severe lymphatic disorder

Through genetic sequencing and targeted treatment, researchers from Children’s Hospital of Philadelphia (CHOP) have resolved a severe lymphatic disorder in a young woman with kaposiform lymphangiomatosis (KLA), a complex and rare disorder that causes lymphatic vessels around the heart and lung to leak fluid, causing breathing difficulties, infections, and often death. The treatment, which the […]

Lifestyle

Vitamin D exposure in utero might minimize high blood pressure risk for children born to mothers with preeclampsia

Children appear to be at greater risk of having high blood pressure when their mothers had the high blood pressure condition called preeclampsia during pregnancy—but this adverse association may be reduced or even eliminated for children who were exposed to higher levels of vitamin D in the womb, according to a study from researchers at […]

Lifestyle

Cannabis use prompts need for more anesthesia during surgery, increases pain

Not only might cannabis users require more anesthesia during surgery than non-users, they may have increased pain afterwards and use higher doses of opioids while in the hospital, suggests first-of-its kind research being presented at the ANESTHESIOLOGY 2020 annual meeting. Adding to the growing body of research that shows patients who use cannabis have higher […]

Lifestyle

Acupuncture before surgery means less pain, significantly fewer opioids for Veterans

Veterans who have acupuncture before surgery report less pain and need far fewer opioids to manage their discomfort, according to a randomized, controlled study being presented at the ANESTHESIOLOGY 2020 annual meeting. Veterans who received acupuncture also reported they were more satisfied with their pain control than those who did not. “Six percent of patients […]

Lifestyle

Preliminary results of two large immune therapy studies show promise in advanced cervical cancer

Preliminary results from two independent, phase II clinical trials investigating a new PD-1 (programmed cell death protein 1)-based immune therapy for metastatic cervical cancer suggest potential new treatment options for a disease that currently has limited effective options and disproportionately impacts younger women. David O’Malley, MD, of The Ohio State University Comprehensive Cancer Center—Arthur G. […]

Lifestyle

‘Repliclones’ fuel perplexing persistence of HIV in the blood of some patients on therapy

Increasingly, UPMC’s chief of infectious diseases—a well-regarded expert in HIV/AIDS—is contacted by a perplexed physician describing a patient with HIV who insists they are adhering to the daily medication regimen meant to keep the virus in check, but testing says otherwise. Virus is still showing up in the patient’s blood, something clinicians believe can’t happen […]

Lifestyle

Virtual driving assessment shows feasibility, validity, efficiency as part of licensing

Researchers from Children’s Hospital of Philadelphia (CHOP) and the University of Pennsylvania’s Annenberg Public Policy Center have demonstrated the feasibility of incorporating a virtual driving assessment system into the driver’s licensing process in Ohio. In a report published today in Health Affairs, the researchers also assessed the validity of the tool in identifying likely on-road […]